Potential Conscientious Objection to mRNA Technology as Preventive Treatment for COVID-19


  • Patrick Provost Département de microbiologie-infectiologie et d'immunologie, Faculté de médecine, Université Laval, Québec, QC, Canada https://orcid.org/0000-0002-6099-6562
  • Nicolas Derome Département de biologie, Institut de biologie intégrative et des systèmes, Université Laval, Québec, QC, Canada
  • Christian Linard Université du Québec à Trois-Rivières
  • Bernard Massie Retired general manager of the Human Health Therapeutics portfolio, National Research Council of Canada, Montreal, QC, Canada
  • Jean Caron Département de Psychiatrie, Université McGill, QC, Canada




Conscientious objection, messenger RNA technology, preventive treatment for COVID-19


In the context of mass vaccination campaigns, the most widely used vaccines in Western countries are based on messenger RNA (mRNA). Some countries have imposed mandatory vaccination and many others have required a vaccination passport to access public transportation and many activities, producing systemic discrimination, social exclusion, segregation, and stigmatization against non-vaccinated individuals. This paper aims to present several scientific uncertainties on which, conscientious objectors to mRNA injections as a preventive treatment for COVID-19, could rely. Scientific data are presented on mRNA vaccines, which consist in mRNAs wrapped in lipid nanoparticles. Never used as a prophylactic drug, artificial mRNAs delivered to our cells forces them to express, against their nature, a biologically active viral protein. Unlike a drug produced in a pharmaceutical factory and formulated at a known dose and a well-defined protein product profile, the mRNA vaccine acts as a pro-drug encoding for the viral Spike protein of the virus to be produced by our own cells; both the dose and the quality of the proteins produced are unknown. We also ignore the distribution of the lipid nanoparticles carrying this mRNA in our body. We consider that the “conscientious objection” raised by the above considerations is a reason enough to refuse mRNA vaccines or similar technologies as a preventive treatment against COVID-19.


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How to Cite

Provost, P., Derome, N., Linard, C., Massie, B., & Caron, J. (2022). Potential Conscientious Objection to mRNA Technology as Preventive Treatment for COVID-19. International Journal of Vaccine Theory, Practice, and Research, 2(2), 445–454. https://doi.org/10.56098/ijvtpr.v2i2.41